AI medical interpreter for clinical genetics and genomics
Opalite gives genetic counselors and medical geneticists real-time interpretation in 150+ languages and dialects, 24/7, from the pretest pedigree to results disclosure and cascade testing calls.
Today's challenge
What gets in the way of interpretation in clinical genetics today
A vague word for an uncertain variant
The telephone interpreter renders "variant of uncertain significance" as a loose phrase about a strange result.
A daughter relaying her mother's BRCA1 result
An adult daughter softens the cancer risk figures in her mother's BRCA1 result.
Blank branches on the pedigree
Without a matched interpreter, the counselor leaves the grandparents' causes of death blank on the family tree.
Cost of inaction
Language interpretation remains a gap in clinical genetics and genomics
4%
of U.S. genetic counselors reported fluency in Spanish in a 2024 national professional survey.
Source: Spanish language opportunities in genetic counseling training programs in the United States
2% vs. 5%
of hereditary cancer genetics referrals and of all adult members had a non-English primary language at Kaiser Permanente Northwest.
79.7%
of genetic counselors in a 2020 national survey named interpreters' unfamiliarity with genetic terms as a constraint.
Meet Opalite.
Real-time AI medical interpretation in 150+ languages and dialects, connecting providers and patients in seconds.
- Works on the devices care teams already carry: phones, tablets, computers, and telehealth platforms
- Integrates with all EHRs
- Built for HIPAA-compliant healthcare
- SOC 2 Type II attested security controls
Workflow
How Opalite fits genetic counseling
| Stage | What happens | How Opalite supports it |
|---|---|---|
| Pretest counseling and consent | Family history, pedigree, test options, secondary-findings choices | Two-way interpretation in the clinic room, or over Zoom and Microsoft Teams for telegenetics |
| Results disclosure | Positive, negative and uncertain results, screening and surgery options | Guardian checks each interpreted sentence about risk figures and next steps. |
| Cascade testing follow-up | Calls about which relatives to inform and where they can be tested | Phone interpretation on any line, including landlines, for the patient's follow-up calls |
Clinical use cases
Interpret the conversations that matter most
Taking the family history
EnglishHas anyone in your family, on your mother's or father's side, had cancer before age 50?
Spanish¿Alguien en su familia, del lado de su madre o de su padre, ha tenido cáncer antes de los 50 años?
Choosing secondary findings
EnglishYou can choose whether we tell you about findings unrelated to the reason for this test.
Chinese (Mandarin)您可以选择是否让我们告诉您与这次检测目的无关的发现。
Explaining an uncertain variant
EnglishThis change in the gene has an uncertain meaning, and we will not change your care because of it today.
Arabicهذا التغيّر في الجين غير واضح المعنى، ولن نغيّر رعايتك الطبية اليوم بسببه.
Risk to brothers, sisters and children
EnglishYour brothers, sisters and children each have a 50% chance of carrying this same variant.
SpanishSus hermanos, hermanas e hijos tienen cada uno un 50% de probabilidad de tener esta misma variante.
A high-chance prenatal screen
EnglishThis screening result shows a higher chance, but it does not mean your baby has the condition.
Chinese (Mandarin)这个筛查结果显示风险较高，但并不代表您的宝宝一定有这种疾病。
Pricing
Pricing for genetics services
Long consent talks, no meter. Genetics teams pay one predictable rate for their service, with no per-minute charge on sequencing consent or uncertain-result explanations.
In your area
25.5 million people in the U.S. speak English less than “very well.”
How many live near you? Search your state, ZIP code, or town.
Darker states have a higher share of residents who speak English less than very well; shading is logarithmic, relative to the highest-share state.
| State | Share | People |
|---|---|---|
| California | 17.2% | 6,377,000 |
| Texas | 13.1% | 3,532,000 |
| New York | 13.1% | 2,486,000 |
| New Jersey | 12.2% | 1,060,000 |
| Florida | 11.8% | 2,389,000 |
| Hawaii | 11.2% | 152,900 |
| Nevada | 11.1% | 320,200 |
| Massachusetts | 9.5% | 631,900 |
| New Mexico | 8.7% | 172,700 |
| Illinois | 8.5% | 1,027,000 |
| Connecticut | 8.4% | 288,200 |
| Rhode Island | 8.4% | 87,250 |
| Arizona | 8.1% | 542,400 |
| Washington | 7.6% | 547,600 |
| Maryland | 7.1% | 411,700 |
| Virginia | 5.8% | 469,000 |
| Colorado | 5.5% | 295,600 |
| Georgia | 5.4% | 541,600 |
| District of Columbia | 5.4% | 34,600 |
| Oregon | 5.4% | 214,100 |
| Nebraska | 5.1% | 93,560 |
| Delaware | 4.9% | 45,460 |
| Utah | 4.7% | 140,000 |
| Kansas | 4.5% | 124,100 |
| Minnesota | 4.5% | 239,600 |
| North Carolina | 4.5% | 439,200 |
| Pennsylvania | 4.4% | 544,000 |
| Alaska | 4.3% | 29,650 |
| Oklahoma | 3.8% | 142,200 |
| Idaho | 3.7% | 62,850 |
| Iowa | 3.4% | 100,800 |
| Michigan | 3.4% | 318,900 |
| Arkansas | 3.2% | 90,380 |
| Indiana | 3.2% | 200,900 |
| Tennessee | 3.1% | 197,500 |
| Wisconsin | 3.0% | 164,200 |
| Louisiana | 2.8% | 123,500 |
| South Carolina | 2.8% | 132,700 |
| Ohio | 2.5% | 281,500 |
| Kentucky | 2.4% | 101,800 |
| New Hampshire | 2.4% | 31,410 |
| Missouri | 2.1% | 123,000 |
| Alabama | 2.1% | 98,720 |
| South Dakota | 1.9% | 15,800 |
| North Dakota | 1.9% | 13,810 |
| Wyoming | 1.8% | 9,923 |
| Mississippi | 1.6% | 44,870 |
| Maine | 1.4% | 18,140 |
| Vermont | 1.3% | 7,705 |
| Montana | 0.8% | 7,731 |
| West Virginia | 0.6% | 11,060 |
Source: U.S. Census Bureau ACS (states 2017-2021; metros 2024 or 2020-2024). Limited English: residents 5+ who speak English less than “very well.”
FAQ
Frequently asked questions
Explore
Where clinical genetics and genomics is practiced
Related
See Opalite in clinical genetics.
Run a pretest family history or a results disclosure in your patients' languages.